Genomic Feature and Variation Ontology

The Genomic Feature and Variation Ontology (GFVO) is modeled to represent genomic data using the Resource Description Format (RDF) or Linked Data using JSON (JSON-LD). It is captures the contents of data files that adhere to the Generic Feature Format Version 3 (GFF3,, the General Transfer Format (GTF,, the Genome Variation Format Version 1 (GVF,, and the Variant Call Format (VCF,, as well as the FASTA format ( The creation of the ontology was inspired by previous work of Robert Hoehndorf on RDF2OWL ( NOTE: GFVO in BioPortal is a simplified version without ontology imports and having class/property equivalences removed. The full ontology is available at:



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